Orthopaedic Joint Replacement Market

Global Industry Analysis (2018 – 2021) – Growth Trends and Market Forecast (2022 – 2026)

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Artificial Joints Enhance Quality of Life

Painless movement becomes the goal of life as people age, and if the joint functionality is lost, knee, and hip prostheses that offer a solution are among the most sought-after, and successful surgical procedures performed today. Several conditions can cause joint pain, and disability and lead patients to consider a joint replacement surgery. Total joint replacement is a surgical procedure in which parts of an arthritic, or damaged joint are removed, and replaced with a metal, plastic, or ceramic device called a prosthesis. The prosthesis is designed to replicate (mimic the shape) the movement of a natural, normal, healthy joint in addition to achieve more natural kinematics, and optimised implant positioning.

Hip and thigh, and knee and lower leg replacements are the most commonly performed joint replacements, as indicated by the American Academy of Orthopaedic Surgeons. However, a replacement surgery can be performed on other joints as well, including the foot and ankle, hand and wrist, shoulder, elbow, neck, and back. The number of orthopaedic surgeries is ever-increasing, strongly supported by rapid technological improvements, and emergence of innovative surgical techniques. Procedures such as hip resurfacing, mini stem total hip arthroplasty, dual mobility total hip arthroplasty, cement-less knee total knee arthroplasty, implant surface modification, and robotic assisted surgery continue to add to the safety, and reliability of orthopaedic joint replacement. Moreover, custom implants, and 3D implants further elevate the scope of expansion for the orthopaedic joint replacement market.

Long-term Outcome, and Success Rate of Joint Replacement

According to the American Academy of Orthopedic Surgeons (AAOS), 90% of people with a replaced knee have reported significant reduction in pain. For many, it helps them stay active, and may enable them to return to routine activities they previously enjoyed such as walking, and golf. A study published in the Journal of Bone and Joint Surgery shows that 5.26% of individuals in the US have had total hip replacement surgery by the age of 80 years, while 10.4% underwent total knee replacement surgery by almost the same age. In both instances, the proportion of female patients is higher. The AAOS notes that over 90% of replaced knees are still functioning after 15 years of the surgery. According to a research published in 2019, 82% of total knee replacements are still functional even after 25 years of the surgery.

High Incidence of Musculoskeletal Conditions, and Better Diagnostics Improve Changes for Higher Uptake

Rising musculoskeletal diagnoses, and high prevalence of osteoporosis fractures are boosting the number of orthopaedic procedures worldwide. According to the World Health Organization (WHO) estimates, about 20–33% of people across the globe live with a painful musculoskeletal condition. The International Osteoporosis Foundation states that there were an estimated 9 million osteoporosis fracture cases in 2000, of which around 1.6 million were at the hip, 1.7 million were at the forearm, and 1.4 million were clinical vertebral fractures. More than half, about 51%, of these are in Europe, and the Americas while the remainder were noted in the Western Pacific, and Southeast Asian regions.

Precision, and Risk-reducing Technological Advancements Fuel Patient Acceptance of Joint Replacement

Noteworthy technological advancements impacting orthopaedic surgical interventions are autonomous surgical robots, 3D printed surgical planning models and instruments, and augmented reality assisted surgeries. In 2019, Zebra Medical Vision was acquired by DePuy Synthese (J&J) to develop, and commercialise the 3D imaging technology for orthopaedic surgery. In February 2020, Globus Medical announced its first procedure using HEDRON IA implant, a 3D printed integrated ALIF spacer that leverages anchors, or screws for vertebral body fixation. This technology offers smaller incisions, and lesser exposure to potential complications during implanting procedure. Thus, technological advances are transforming orthopaedic interventions as the promise of precision, and risk-free procedures builds up patient confidence.

Safety and Complications

Knee replacement surgery is relatively safe, and effective for most people. According to the AAOS, fewer than 2% of people experience severe complications such as an infection, blood clot, deep vein thrombosis, osteolysis, stiffness, and pain. Nearly 5% of people will need a revision within the first 10 years. Of these, 29.8% are due to the joint coming loose, 14.8% due to infection, and 9.5% due to pain. According to The Journal of Bone & Joint Surgery, the number of revised total knee replacements is predicted to reach 268,200 in 2030, representing a 600% increase over the number of procedures performed in 2005.

Advanced Treatments

Several orthopaedic implant manufacturers - Smith & Nephew, Wright Medical Technology, DePuy, Biomet, Medacta, and Zimmer - offer Patient Specific Instrumentation (PSI systems). These systems can be used for total joint arthroplasty, or unicompartmental joint arthroplasty. Preoperative 3D imaging (CT scan, or MRI) is used to model the joint anatomy and design a personalised surgical plan with respect to bone resection, component positioning, and alignment. There is high success rate using better, and longer lasting biocompatible machines. Space age bio-materials and computer assisted improvements are now helping patients live a better and more active life. However, soft tissue imbalance, equal and rectangular extension and flexion gaps, and medial and lateral compartment loads are the major causes of dissatisfaction.

Regulations and Standards

There are Medical Devices Act/Regulations/Classifications by the various countries. Chief is Standards by ISO/TC 150/SC 4 for bone, and joint replacements. EndoLab, BSI, testing and accreditation companies ensure these standards are met. According to a study published in The Journal of Rheumatology, total hip arthroplasty may increase by 284% in 2040 to 1,429,000 replacements; total knee arthroplasty to increase by 401% in 2040 to 3,416,000 replacements, with replacements occurring slightly more frequently in women and in individuals aged 45–84 years. International Society of Orthopaedic Surgery and Traumatology (SICOT), and World Orthopaedic Concern (WOC) promote, and work for advancement of the science, and art of orthopaedics, and traumatology at international level.

Leading Orthopaedic Device Companies in Global Market

Stryker, J&J (Orthopaedics), Zimmer Biomet, Smith & Nephew (Sports Medicine, Trauma, and Reconstruction), Medtronic (Spine Division), Colfax Corp., DJO Global, Wright Medical, Orthofix Medical, ConMed (Orthopaedic Surgery), DePuy Synthes, NuVasive, Globus Medical, Össur, Integra LifeSciences, and Wright Medical are some of the most prominent players in the global orthopaedic joint replacement market.

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