Fairfield Market Research Bone Void Fillers Market Size, Sales Analysis, Opportunity 2029

Bone Void Fillers Market

Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2023-2030 - By Product, Technology, Grade, Application, End-user, Region: (North America, Europe, Asia Pacific, Latin America and Middle East and Africa)

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Industry: Pharmaceuticals & Biotechnology

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Preliminary research of Fairfield Market Research indicates a promising growth outlook for global bone void fillers market that recorded the revenue of around US$2.5 Bn in the year 2021.

Frequent New Launches Remain the Key Driving Force for Bone Void Fillers Market

The rising incidence of various bone illnesses, including bone tumors and infections, is responsible for expanding the market for bone void fillers. The need for goods to treat these injuries is also predicted to increase due to an ageing population that is more prone to fractures, and bone injuries. Additionally, during the projected period, the expansion of bone void fillers market is anticipated to be aided by the rising demand for antibiotic-eluting fillers for bone and the rising number of new product launches by industry participants. For instance, Orthofix stated in September 2021 that Opus Mg set, a magnesium-based settable bone void filler for orthopedic treatments would be available. The bone void fillers market revenue is anticipated to rise over time as a result of such a way product introduction.

Increased prevalence of orthopedic diseases like osteoarthritis, osteoporosis, scoliosis, bone tumors, and bone infections; increased R&D activities in the bone void fillers market; rise in funding from private and public organizations for the development of the healthcare sector and research centers, and rise in the senior population are the main factors driving the growth of the global bone void fillers market size. The United Nations estimates that 727 million people worldwide will be 65 or older in 2020. By 2050, it was predicted that there would be 1.5 billion older adults worldwide. In addition, the World Health Organization (WHO) predicted that by 2030, one in six individuals worldwide would be 60 years of age or older. For instance, the Journal of EClinical Medicine stated in 2020 that knee osteoarthritis affects about 22% of people over the age of 40.

Bone Void Fillers Market: COVID-19 Impact

Due to postponed and canceled elective orthopedic operations, COVID-19 has decreased the need for bone fillers. Due to the COVID-19 pandemic, major market companies saw a considerable revenue reduction. Sales of synthetic fillers, including demineralized bone matrix (DBM) and other fillers used in bone injuries, were negatively impacted by the government restrictions, which led to a decrease in surgical procedures, supply chain disruptions, and other significant parameters, particularly in the first half of 2020. The bone void fillers market experienced a drop in revenue of 8.9% in 2020.

Increasing Adoption of Synthetic BVF to Drive Bone Void Fillers Market Growth

The expansion of bone void fillers market is anticipated to be fueled by the rising use of artificial bone void fillers such as calcium sulfate and tricalcium phosphate. These filters have several benefits over other sources of bone graft substitutes, including a lower risk of morbidity, high sterility, and an endless supply. As a result, demand is expected to rise during the forecast period. Tri-calcium phosphate, an osteoconductive calcium phosphate that is thought to have the most chemical similarities to human bone and is employed increasingly as bone void fillers, makes up synthetic bone void fillers. Major firms like BONESUPPORT AB and Biocomposites introduced their products in the synthetic market. Due to the increased use of these businesses' products, they have recently seen significant growth. These businesses recently got permission for their products, which have been promoted in numerous European nations. For instance, BONESUPPORT AB was awarded the U.S. CERAMENT BVF has received Food and Drug Administration (FDA) approval for use as a bone void filler. These new introductions are anticipated throughout the projected period to fuel the expansion of bone void fillers market.

Launch of Antibiotic Eluting Fillers Supplement Bone Void Fillers Market Revenue

Clinical restrictions, including bone infection following surgery, have heightened interest in antibiotic-eluting void fillers. The market participants are concentrating on stepping up R&D efforts and launching antibiotic-eluting void fillers, which have also decreased bone infection while undergoing treatment. In addition to having a sizable number of items in the pipeline, BONESUPPORT AB has acquired permission for antibiotic-eluting void fillers that are now on the market. Additionally, increased attention of the market participants to clinical studies for introducing medicines to treat bone illnesses is anticipated to fuel the growth of bone void fillers market. For instance, Elute, Inc. declared in June 2021 that the US had approved the company's first clinical trial. FDA approves the use of its antibiotic-eluting void filler. This was the first FDA approval for treating bone infections in patients with EP Granules with Tobramycin. It is anticipated that introducing such cutting-edge products will fuel the expansion of bone void fillers market during the projection period.

Underpenetration, and Clinical Limitations Restrict Expansion of Bone Void Fillers Market

Bone void-filling materials have decreased due to increased clinical restrictions and inadequate penetration. Due to the considerable hazards involved, which include unfavorable tissue reactions, inadequate or nonexistent bone development, soft tissue and bone infections, and breakdown of the fillers with or without particle production, their adoption has decreased. The United States has recalled products due to the rising risks posed by these additives. FDA, which has a negative effect on brands' reputations and competitors' positions in the market. Researchers claim that the widespread use of autogenous and allograft bone transplantation prevents the widespread use of these fillers. Furthermore, the intrusiveness of these fillers might prevent their widespread use.

Calcium Matrix Category to Dominate Bone Void Fillers Market with Properties Linked to Antibacterial Qualities

Based on product type, the bone void fillers market is segmented into the demineralized bone matrix, collagen matrix, calcium matrix, tri-calcium phosphate and others. The calcium matrix category held the largest market share in 2021 and increase significantly over the next several years. The rise is linked to its antibacterial qualities, which result in better outcomes seen by users in the treatment of lower-extremity osteomyelitis. Moreover, the segment is anticipated to grow over the projected period because of increased product releases and artificial void fillers such as calcium sulfate. On the other hand, it is anticipated that the demineralized bone matrix segment will expand significantly throughout the projected period. The demineralized bone matrix has a significant presence in the market participants' product portfolios, which is responsible for the segmental expansion. Additionally, the segmental increase is anticipated to be fueled during the projected period by abundant donor sources, a decline in autograft problems, and a quick recovery time.

Putty Remains the Leading Form-wise Category in Bone Void Fillers Market

Based on the form, the bone void fillers market is segmented into gel, granules, paste, putty and others. The putty category dominated the market over the forecast period. The demand for demineralized bone matrix in the form of putty is anticipated to rise as bone illnesses become more common, particularly in developing nations where DBM usage is higher than other bone void fillers. The long-term segment growth is also anticipated to be fueled by the new product releases by market players. The pasted segment is anticipated to increase significantly during the bone void fillers market forecast period. The paste form is highly preferred and is used more frequently due to its advantages over other forms, including superior osteoconductivity and biocompatibility. Additionally, it is anticipated that demand for paste fillers will increase during the forecast period due to the expanding body of research into the advantages of these materials.

North America’s Primacy Prevails in Bone Void Fillers Market on Account of Innovative Launches

Over the forecast period, it is anticipated that the North American market will account for the largest revenue share. The region's market is anticipated to increase due to the quick uptake of synthetic void fillers, which use various materials, including tri-calcium phosphate and calcium sulfate, and the rising number of innovative products introduced by industry participants. Additionally, it is projected that the market growth in North America would be fueled by an increase in the number of patients with bone disorders, an increase in bone operations, and a strong presence of leading industry participants in the area.

The European bone void fillers market is anticipated to experience stable revenue growth throughout the forecast period due to a growth in the prevalence of orthopedic illnesses, increased knowledge of the use of bone void fillers, a rise in healthcare spending, and a rise in the number of older adults. Additionally, the approval of products used for managing and treating bone voids is expected to expand the market growth in Europe. The growth is attributed to strong and emerging market players like Biocomposites and BONESUPPORT AB. For instance, BONESUPPORT AB reported in April 2020 that the European Union had granted its product offering of STIMULAN a new CE Mark allowing the mixing of antibiotics such vancomycin, gentamicin, and tobramycin in void fillers. It is a therapy option for managing infected bone, and soft tissue.

Global Bone Void Fillers Market: Competitive Landscape

In December 2020, Sunstar's Degradable Solutions branch, which includes the GUIDOR line of bone graft alternatives, was acquired by Collagen Matrix, Inc. Similarly, in November 2020, Stryker acquired Wright Medical to expand the business's line of biologics, which now includes bone void fillers.

A few of the players in the bone void fillers market include BoneSupport AB, Wright Medical Group N.V., DePuy Synthes Co., Stryker, Arthrex Inc., Biocomposites, Zimmer Biomet, Collagen Matrix Inc., Pacific Bioceramics, Johnson and Johnson, NuVasive, Inc.Hoya Corporation, B.Braun Melsungen AG, Heraeus Holding and Smith & Nephew plc.

Regional Classification of the Global Bone Void Fillers Market is Described Below:

North America

  • U.S.
  • Canada


  • Germany
  • France
  • Spain
  • U.K.
  • Italy
  • Russia
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Southeast Asia
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East and Africa

  • GCC
  • South Africa
  • Rest of Middle East and Africa

*Regions and countries are subject to change based on data availability

Key Elements Included In The Study: Global Bone Void Fillers Market

  • Bone Void Fillers Market by Product/Technology/Grade, Application/End-user, and Region
  • Executive Summary (Opportunity Analysis and Key Trends)
  • Historical Market Size and Estimates, Value, 2018 - 2022
  • Market Value at Regional and Country Level, 2023 - 2030
  • Market Dynamics and Economic Overview
  • Market Size in Value, Growth Rates, and Forecast Figures, 2023 - 2030
  • Competitive Intelligence with Financials, Key Developments, and Portfolio of Leading Companies 
  • Regional and Product/Grade/Application/End-user Price Trends Analysis
  • Value Chain and Five Force’s Analysis
  • Regional/Sub-region/Country Market Size and Trend Analysis
  • Company Market Share Analysis and Key Player Profiles

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