Fairfield Market Research Single-use Bioprocessing Market Size, Share Report 2022-2029

Single-use Bioprocessing Market

Global Industry Analysis (2018 - 2021) - Growth Trends and Market Forecast (2022 - 2029)

Published Date: Upcoming | Format:

Industry: Pharmaceuticals & Biotechnology


Request TOC Request Customization * New Version Available

SUS Preferred over Conventional Stainless Steel Systems

Despite being a relatively new technology, single use technology has gained ubiquity in the biopharma sector. Single-use systems (SUS) are gaining wider preference over stainless steel systems in the biotechnology and pharmaceutical markets. Disposable systems are now making the leap from clinical- to commercial-scale bio-manufacturing. Vaccine manufacturers were the early adopters of single use technology as there is no cleaning and no cross-contamination involved. More than 90% of biopharma facilities use at least some single use components and the market for single-use bioprocessing is estimated to reach ~US$ 6 Bn by 2026. The single-use equipment constitutes pre-sterilised disposable bags, tubing, fittings, and connectors. Bioreactor volumes up to 2,000 litre for single use cell culture process are also available.

Flexibility and Cost Competitiveness Make Single-use Systems an Attractive Prospect for Biopharma Manufacturers

In a single-use set up, changing the bag sizes is relatively easy instead of buying, and installing a new stainless steel vessel. Cleaning of the conventional stainless steel vessel is another cumbersome job. Sanitisation of stainless steel vessels is both a time- and cost-intensive activity. Process development, validation, operator training, and then utility consumption only make it more complex and time-consuming. Using plastic disposable technology makes more sense both time-wise and economically. Another strong driver for the single-use bioprocessing technology adoption is the availability of the 2,000 liter bioreactor. Earlier, drugs were produced in a standard batch size of 10,000 liters. However, with the advent of personalised medicines, the batch sizes for many products have reduced to 2,000 liters or even less – hitting the sweet spot for single use. As novel technologies like cell and gene therapies are making their ways, single-use bioprocessing will be deployed from the start, in clinical, process development, and commercial manufacturing suites, pushing the growth prospects of the global single-use bioprocessing market.

Environmental Sustainability and Safety Remain Paramount with Growing Ubiquity of Single Use

Stainless steel bioreactors need huge amounts of water, energy, and cleaning products unlike single-use bioprocessing systems, which makes the latter a sustainable alternative over the former. One of the case studies reveals that swapping to single use has enabled a manufacturer to achieve annual savings of a whopping 1 Mn liters of water, nearly 28,812 kwh electrical power, and over 20 MT of CO2 from their carbon footprint.

However, the seemingly conservative biopharmaceutical industry is still reluctant to give up control of critical process technology. Validation is another major issue as companies raise concerns regarding chemicals released from the polymers in single use products might contaminate the drug. Thus, supply chain security is a critical issue for pharmaceutical manufacturers. Despite all these challenging factors, the adoption of single use has spread to all corners of the globe, worldwide, including some of the relatively less developed markets of South America, the Middle East, Asia, and Africa.

Upstream Workflow a Dominant Segment

The upstream workflow segment dominated the single-use bioprocessing market and accounted for more than half of the global market revenue in 2020. Single-use systems are commonly available for upstream processes (such as cell-culture seeding, and media preparation) vis-à-vis downstream processing. However, rapid technological advancements in the implementation of single-use systems in downstream processing, viz. filtration devices, pumps, and heat exchangers is fueling the segment growth further.

North America Key Revenue Generator; Prolific Growth of Market in Asia Pacific

North America captured ~1/3rd of the global single-use bioprocessing market revenue in 2020 as the region houses a large number of contract manufacturers involved in the implementation of disposables in their workflows. Also, heavy R&D spending by large-scale biopharmaceutical companies contributed to the dominance of the region in the global market. Moreover, patent expiry of several biologics is driving further the North American single-use bioprocessing market. The market in Asia Pacific are growing rapidly as compared to their western counterparts largely on the back of increasing government initiatives in the area, and improving R&D infrastructure, and investments. With pharmaceutical manufacturing powerhouses - China and India, this region is anticipated to register the fastest CAGR during the forecast period.

Key Companies Preparing for Post-COVID-19 Demand Surge

The anticipation of the need for vaccinating billions of people against COVID-19 has resulted in soaring demand for bioprocessing equipment in recent quarters. Avantor is investing to boost single-use bioprocessing equipment production capacity. Wuxi Biologics, and Chine CDMO kick-started facility employing nine 4,000 litre single-use bioreactors in early 2021. Earlier in 2020, Danaher bought GE Healthcare’s biopharma business for US$ 20 Bn to consolidate its strong industry position. Besides, Thermo Fisher Scientific, Inc., Merck KGaA, Sartorius AG, Pall Corporation, Eppendorf AG, Rentschler Biopharma SE, Lonza, Meissner Filtration Products, Inc., JM BioConnect, Boehringer Ingelheim GmbH, Danaher Corporation, Avantor Inc., and Kuhner AG are some of the most prominent players actively participating in global single-use bioprocessing market landscape.

Key Elements Included In The Study: Global Single-use Bioprocessing Market

  • Single-use Bioprocessing Market by Product/Technology/Grade, Application/End-user, and Region
  • Executive Summary (Opportunity Analysis and Key Trends)
  • Historical Market Size and Estimates, Value, 2018 - 2021
  • Market Value at Regional and Country Level, 2022 - 2029
  • Market Dynamics and Economic Overview
  • Market Size in Value, Growth Rates, and Forecast Figures, 2022 - 2029
  • Competitive Intelligence with Financials, Key Developments, and Portfolio of Leading Companies 
  • Regional and Product/Grade/Application/End-user Price Trends Analysis
  • Value Chain and Five Force’s Analysis
  • Regional/Sub-region/Country Market Size and Trend Analysis
  • Company Market Share Analysis and Key Player Profiles

Post Sale Support, Research Updates & Offerings

We value the trust shown by our customers in Fairfield Market Research. We support our clients through our post sale support, research updates and offerings.

  • The report will be prepared in a PPT format and will be delivered in a PDF format.
  • Additionally, Market Estimation and Forecast numbers will be shared in Excel Workbook.
  • If a report being sold was published over a year ago, we will offer a complimentary copy of the updated research report along with Market Estimation and Forecast numbers within 2-3 weeks’ time of the sale.
  • If we update this research study within the next 2 quarters, post purchase of the report, we will offer a Complimentary copy of the updated Market Estimation and Forecast numbers in Excel Workbook.
  • If there is a geopolitical conflict, pandemic, recession, and the like which can impact global economic scenario and business activity, which might entirely alter the market dynamics or future projections in the industry, we will create a Research Update upon your request at a nominal charge.

Disclaimer:

  • The segmentation/company profiles/countries depicted above may vary in the actual report.

Request Table of Contents

Our Research Methodology

Considering the volatility of business today, traditional approaches to strategizing a game plan can be unfruitful if not detrimental. True ambiguity is no way to determine a forecast. A myriad of predetermined factors must be accounted for such as the degree of risk involved, the magnitude of circumstances, as well as conditions or consequences that are not known or unpredictable. To circumvent binary views that cast uncertainty, the application of market research intelligence to strategically posture, move, and enable actionable outcomes is necessary.

View Methodology
Fairfield Quality assured
Fairfield Confidentiality assured
Fairfield Custom research services