Gene Synthesis Market

Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2023-2030 - By Product, Technology, Grade, Application, End-user, Region: (North America, Europe, Asia Pacific, Latin America and Middle East and Africa)

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Industry: Pharmaceuticals & Biotechnology


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Gene synthesis market is likely to exhibit a promising growth curve as far as the short-term outlook is considered. The report will uncover the insights into how the market growth will unfold in the next few years.

Rising Prevalence of Chronic Diseases and Adoption of Gene Therapy to Bolster Gene Synthesis Market Growth

Rising research and development activities in the field of next generation sequencing and genomics coupled with increasing preference for personalized medicine remain instrumental in driving growth of the gene synthesis market. Gene synthesis is also gaining traction in molecular diagnosis to treat genetic and infectious diseases. By leveraging this method, genetic variations can be detected thus predicting the response towards certain class of drugs. In this backdrop, personalized medicine has gained high traction backed by a patient-centric approach to govern and ensure patient success.  

On the back of rising prevalence of chronic diseases, the demand for effective and new therapies has increased considerably. By using gene therapy, management of endemic and infectious diseases can be improved. Moreover, it also allows researchers to understand drug resistance and screen targets for developments of vaccines and new therapeutics. This factor has attracted researchers as it can treat infectious diseases by applying recombinant DNA technology, single chain antibodies and DNA & RNA ribozyme. This has further called for gene synthetic constructs to accelerate the development of gene therapy. These aspects continue to influence the growth of the gene synthesis market on the global front.

Adoption for Highly Accurate Diagnostics Complements Gene Synthesis Market Growth

Ongoing advancements in gene synthesis or synthetic DNA technology have opened breakthroughs and are considered as a viable and effective solution to address increasing concerns apropos to growing number of pathogens and associated diseases, including the threat of the global COVID 19 pandemic. As new strains of Sars-CoV-2 have surfaced, the demand for targeted therapies has increased thus fuelling the adoption of novel technologies such as gene synthesis to aid in screening. In addition, several research institutions and facilities have been relying on gene synthesis technique to develop accurate diagnostics for the treatment of new diseases. For instance, the National Institute of Standards and Technology (NIST) adopted gene synthesis to develop new gene fragments from Sars-CoV-2 virus. This is in view to support medical testing providers develop highly reliable and accurate diagnostics for the disease. Such developments are expected to augur well for the growth of the gene synthesis market.

North America’s Dominance Prevails in Gene Synthesis Market, Asia Pacific Follows

Developed economies in North America are expected to account for a significant share in the gene synthesis market. Countries such as Canada, and United States are poised to lead the market in the coming years. This is mainly owing to rising prevalence of chronic and genetic ailments including ageing and cancer among others. Moreover, this has triggered the demand for personalized and targeted medicine in turn paving new avenues for the gene synthesis market in North America. Furthermore, macro level factors such as favourable healthcare infrastructure, government support, rising investments in research and development in the medical field and strong economic growth have been influential in driving the adoption of gene synthesis in the region. For instance, in 2021, a budget of around US$6.5 Bn was allocated to the National Cancer Institute of United States to carry out targeted research for cancer alone. Such allocation of high amount funding to institutions is expected to complement the growth of the gene synthesis research activities in the region, making it an attractive regional market.

On the contrary, Asia Pacific is likely to project high lucrativeness with regards to gene synthesis. The region has been reflecting acceptance towards innovations by leveraging new technologies. To improve the existing medical and healthcare scenario, companies are focusing developing new screening systems to diagnose and treat chronic disorders. In addition, emerging economies in Asia Pacific have been eyed upon by major players as a lucrative soil with a plethora of opportunities. In wake of this judgement, several healthcare companies are tapping the Asian land to assess its untapped potential. This has, in turn given rise to several research activities presenting opportunities for biological functionality. As a consequence, various synthetic biology and gene synthesis protocols were prompted in the region. Moreover, increasing population and a higher percentage of geriatric population coupled with rising illnesses, need for therapeutic developments and replication of DNA continue to influence the gene synthesis market in Asia Pacific.

Gene Synthesis Market: Competitive Landscape

Major players in the gene synthesis market have been involved in new launches, collaborations, and alliances for consolidating their position. For instance, in 2020, Japanese pharmaceutical company Takeda Pharmaceuticals and US-based Codexis entered a strategic collaboration. As per this alliance, Codexis will offer gene synthesis services to Takeda to support the development of novel gene therapies to treat rare genetic disorders. In the other hand, in 2022, an early access program was launched by DNA Script for its SYNTAX system customers. Under this program, organizations could receive early access to new advancements in enzymatic DNA synthesis. Same year in July, OraSure Technologies introduced OmniGene Gut RNA and DNA product referred to as OMR-205. This product was specifically developed for gut microbiome researchers.

A few of the major players in gene synthesis market include Merck KGaA, Eurofins Genomics, GenScript, Genewiz Inc., Thermo Fisher Scientific Inc., ProteoGenix, Integrated DNA Technologies Inc., Brooks Automation Inc., OriGene Technologies Inc., Biomatik, and Twist Bioscience.

Regional Classification of the Global Gene Synthesis Market is Listed Below:

North America

  • U.S.
  • Canada

Europe

  • Germany
  • France
  • Spain
  • U.K.
  • Italy
  • Russia
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Southeast Asia
  • Rest of Asia Pacific

 Latin America

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East and Africa

  • GCC
  • South Africa
  • Rest of Middle East & Africa

*Regions and countries are subject to change based on data availability.

Key Elements Included In The Study: Global Gene Synthesis Market

  • Gene Synthesis Market by Product/Technology/Grade, Application/End-user, and Region
  • Executive Summary (Opportunity Analysis and Key Trends)
  • Historical Market Size and Estimates, Value, 2018 - 2022
  • Market Value at Regional and Country Level, 2023 - 2030
  • Market Dynamics and Economic Overview
  • Market Size in Value, Growth Rates, and Forecast Figures, 2023 - 2030
  • Competitive Intelligence with Financials, Key Developments, and Portfolio of Leading Companies 
  • Regional and Product/Grade/Application/End-user Price Trends Analysis
  • Value Chain and Five Force’s Analysis
  • Regional/Sub-region/Country Market Size and Trend Analysis
  • Company Market Share Analysis and Key Player Profiles

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1. Executive Summary
     1.1. Global Gene Synthesis Market Outlook, 2018 - 2030 (US$ Million)
     1.2. Global Gene Synthesis Market Incremental Opportunity, 2018 - 2030 (US$ Million)
     1.3. Key Industry Trends

2. Market Overview
     2.1. Market Definitions and Segmentations
     2.2. Market Dynamics
            2.2.1. Drivers
                  2.2.1.1. Driver 1
                  2.2.1.2. Driver 2
            2.2.2. Restraints
                  2.2.2.1. Restraint 1
                  2.2.2.2. Restraint 2
            2.2.3. Market Opportunities Matrix
     2.3. Porters Five Forces Analysis
     2.4. Regulatory Guidelines & Reimbursement Scenario
     2.5. Covid-19 Impact Analysis

3. Global Gene Synthesis Market Outlook, 2018 - 2030
     3.1. Global Gene Synthesis Market Outlook, by Product & Service, Value (US$ Mn), 2018 - 2030
            3.1.1. Key Highlights
                  3.1.1.1. Consumables
                  3.1.1.2. Services
                  3.1.1.3. Software
            3.1.2. BPS Analysis/Market Attractiveness Analysis
     3.2. Global Gene Synthesis Market Outlook, by Method, Value (US$ Mn), 2018 - 2030
            3.2.1. Key Highlights
                  3.2.1.1. Solid Phase Synthesis
                  3.2.1.2. Chip based Synthesis
                  3.2.1.3. PCR based Enzyme Synthesis
                  3.2.1.4. Others
            3.2.2. BPS Analysis/Market Attractiveness Analysis
     3.3. Global Gene Synthesis Market Outlook, by Application, Value (US$ Mn), 2018 - 2030
            3.3.1. Key Highlights
                  3.3.1.1. Diagnostics
                  3.3.1.2. Therapeutics
                  3.3.1.3. Research & Development
            3.3.2. BPS Analysis/Market Attractiveness Analysis
     3.4. Global Gene Synthesis Market Outlook, by End User, Value (US$ Mn), 2018 - 2030
            3.4.1. Key Highlights
                  3.4.1.1. Pharmaceutical & Biotech Companies
                  3.4.1.2. Contract Research Organizations
                  3.4.1.3. Diagnostic Laboratories
                  3.4.1.4. Academic & Research Institutes
                  3.4.1.5. Others
            3.4.2. BPS Analysis/Market Attractiveness Analysis
     3.5. Global Gene Synthesis Market Outlook, by Region, Value (US$ Mn), 2018 - 2030
            3.5.1. Key Highlights
                  3.5.1.1. North America
                  3.5.1.2. Europe
                  3.5.1.3. Asia Pacific
                  3.5.1.4. Rest of the World
            3.5.2. BPS Analysis/Market Attractiveness Analysis

4. North America Gene Synthesis Market Outlook, 2018 - 2030
     4.1. North America Gene Synthesis Market Outlook, by Product & Service, Value (US$ Mn), 2018 - 2030
            4.1.1. Key Highlights
                  4.1.1.1. Consumables
                  4.1.1.2. Services
                  4.1.1.3. Software
                  4.1.1.4. Others
            4.1.2. BPS Analysis/Market Attractiveness Analysis
     4.2. North America Gene Synthesis Market Outlook, by Method, Value (US$ Mn), 2018 - 2030
            4.2.1. Key Highlights
                  4.2.1.1. Solid Phase Synthesis
                  4.2.1.2. Chip based Synthesis
                  4.2.1.3. PCR based Enzyme Synthesis
                  4.2.1.4. Others
            4.2.2. BPS Analysis/Market Attractiveness Analysis
     4.3. North America Gene Synthesis Market Outlook, by Application, Value (US$ Mn), 2018 - 2030
            4.3.1. Key Highlights
                  4.3.1.1. Diagnostics
                  4.3.1.2. Therapeutics
                  4.3.1.3. Research & Development
            4.3.2. BPS Analysis/Market Attractiveness Analysis
     4.4. North America Gene Synthesis Market Outlook, by End User, Value (US$ Mn), 2018 - 2030
            4.4.1. Key Highlights
                  4.4.1.1. Pharmaceutical & Biotech Companies
                  4.4.1.2. Contract Research Organizations
                  4.4.1.3. Diagnostic Laboratories
                  4.4.1.4. Academic & Research Institutes
                  4.4.1.5. Others
            4.4.2. BPS Analysis/Market Attractiveness Analysis
     4.5. North America Gene Synthesis Market Outlook, by Country, Value (US$ Mn), 2018 - 2030
            4.5.1. Key Highlights
                  4.5.1.1. U.S.
                  4.5.1.2. Canada
            4.5.2. BPS Analysis/Market Attractiveness Analysis

5. Europe Gene Synthesis Market Outlook, 2018 - 2030
     5.1. Europe Gene Synthesis Market Outlook, by Product & Service, Value (US$ Mn), 2018 - 2030
            5.1.1. Key Highlights
                  5.1.1.1. Consumables
                  5.1.1.2. Services
                  5.1.1.3. Software
                  5.1.1.4. Others
            5.1.2. BPS Analysis/Market Attractiveness Analysis
     5.2. Europe Gene Synthesis Market Outlook, by Method, Value (US$ Mn), 2018 - 2030
            5.2.1. Key Highlights
                  5.2.1.1. Solid Phase Synthesis
                  5.2.1.2. Chip based Synthesis
                  5.2.1.3. PCR based Enzyme Synthesis
                  5.2.1.4. Others
            5.2.2. BPS Analysis/Market Attractiveness Analysis
     5.3. Europe Gene Synthesis Market Outlook, by Application, Value (US$ Mn), 2018 - 2030
            5.3.1. Key Highlights
                  5.3.1.1. Diagnostics
                  5.3.1.2. Therapeutics
                  5.3.1.3. Research & Development
            5.3.2. BPS Analysis/Market Attractiveness Analysis
     5.4. Europe Gene Synthesis Market Outlook, by End User, Value (US$ Mn), 2018 - 2030
            5.4.1. Key Highlights
                  5.4.1.1. Pharmaceutical & Biotech Companies
                  5.4.1.2. Contract Research Organizations
                  5.4.1.3. Diagnostic Laboratories
                  5.4.1.4. Academic & Research Institutes
                  5.4.1.5. Others
            5.4.2. BPS Analysis/Market Attractiveness Analysis
     5.5. Europe Gene Synthesis Market Outlook, by Country, Value (US$ Mn), 2018 - 2030
            5.5.1. Key Highlights
                  5.5.1.1. Germany
                  5.5.1.2. France
                  5.5.1.3. U.K.
                  5.5.1.4. Italy
                  5.5.1.5. Spain
                  5.5.1.6. Rest of Europe
            5.5.2. BPS Analysis/Market Attractiveness Analysis

6. Asia Pacific Gene Synthesis Market Outlook, 2018 - 2030
     6.1. Asia Pacific Gene Synthesis Market Outlook, by Product & Service, Value (US$ Mn), 2018 - 2030
            6.1.1. Key Highlights
                  6.1.1.1. Consumables
                  6.1.1.2. Services
                  6.1.1.3. Software
                  6.1.1.4. Others
            6.1.2. BPS Analysis/Market Attractiveness Analysis
     6.2. Asia Pacific Gene Synthesis Market Outlook, by Method, Value (US$ Mn), 2018 - 2030
            6.2.1. Key Highlights
                  6.2.1.1. Solid Phase Synthesis
                  6.2.1.2. Chip based Synthesis
                  6.2.1.3. PCR based Enzyme Synthesis
                  6.2.1.4. Others
            6.2.2. BPS Analysis/Market Attractiveness Analysis
     6.3. Asia Pacific Gene Synthesis Market Outlook, by Application, Value (US$ Mn), 2018 - 2030
            6.3.1. Key Highlights
                  6.3.1.1. Diagnostics
                  6.3.1.2. Therapeutics
                  6.3.1.3. Research & Development
            6.3.2. BPS Analysis/Market Attractiveness Analysis
     6.4. Asia Pacific Gene Synthesis Market Outlook, by End User, Value (US$ Mn), 2018 - 2030
            6.4.1. Key Highlights
                  6.4.1.1. Pharmaceutical & Biotech Companies
                  6.4.1.2. Contract Research Organizations
                  6.4.1.3. Diagnostic Laboratories
                  6.4.1.4. Academic & Research Institutes
                  6.4.1.5. Others
            6.4.2. BPS Analysis/Market Attractiveness Analysis
     6.5. Asia Pacific Gene Synthesis Market Outlook, by Country, Value (US$ Mn), 2018 - 2030
            6.5.1. Key Highlights
                  6.5.1.1. China
                  6.5.1.2. Japan
                  6.5.1.3. India
                  6.5.1.4. South Korea
                  6.5.1.5. Australia & New Zealand
                  6.5.1.6. Rest of Asia Pacific
            6.5.2. BPS Analysis/Market Attractiveness Analysis

7. Rest of the World Gene Synthesis Market Outlook, 2018 - 2030
     7.1. Rest of the World Gene Synthesis Market Outlook, by Product & Service, Value (US$ Mn), 2018 - 2030
            7.1.1. Key Highlights
                  7.1.1.1. Consumables
                  7.1.1.2. Services
                  7.1.1.3. Software
                  7.1.1.4. Others
            7.1.2. BPS Analysis/Market Attractiveness Analysis
     7.2. Rest of the World Gene Synthesis Market Outlook, by Method, Value (US$ Mn), 2018 - 2030
            7.2.1. Key Highlights
                  7.2.1.1. Solid Phase Synthesis
                  7.2.1.2. Chip based Synthesis
                  7.2.1.3. PCR based Enzyme Synthesis
                  7.2.1.4. Others
            7.2.2. BPS Analysis/Market Attractiveness Analysis
     7.3. Rest of the World Gene Synthesis Market Outlook, by Application, Value (US$ Mn), 2018 - 2030
            7.3.1. Key Highlights
                  7.3.1.1. Diagnostics
                  7.3.1.2. Therapeutics
                  7.3.1.3. Research & Development
            7.3.2. BPS Analysis/Market Attractiveness Analysis
     7.4. Rest of the World Gene Synthesis Market Outlook, by End User, Value (US$ Mn), 2018 - 2030
            7.4.1. Key Highlights
                  7.4.1.1. Pharmaceutical & Biotech Companies
                  7.4.1.2. Contract Research Organizations
                  7.4.1.3. Diagnostic Laboratories
                  7.4.1.4. Academic & Research Institutes
                  7.4.1.5. Others
            7.4.2. BPS Analysis/Market Attractiveness Analysis
     7.5. Rest of the World Gene Synthesis Market Outlook, by Country, Value (US$ Mn), 2018 - 2030
            7.5.1. Key Highlights
                  7.5.1.1. Latin America
                  7.5.1.2. Middle East & Africa
            7.5.2. BPS Analysis/Market Attractiveness Analysis

8. Competitive Landscape
     8.1. Company Market Share Analysis
     8.2. Company Profiles
            8.2.1. Genewiz
                  8.2.1.1. Company Overview
                  8.2.1.2. Financial Overview
                  8.2.1.3. Product & Service Portfolio
                  8.2.1.4. Recent Developments
*Above details will include, but not be limited to below list of companies based on availability
            8.2.2. ProteoGenix, Inc.
            8.2.3. Thermo Fischer Scientific
            8.2.4. Telesis Bio
            8.2.5. GenScript
            8.2.6. Eurofins Genomics LLC
            8.2.7. Twist Bioscience
            8.2.8. OriGene Technologies, Inc.
            8.2.9. Others

9. Appendix
     9.1. Research Methodology
     9.2. Report Assumptions
     9.3. Acronyms and Abbreviations

Our Research Methodology

Considering the volatility of business today, traditional approaches to strategizing a game plan can be unfruitful if not detrimental. True ambiguity is no way to determine a forecast. A myriad of predetermined factors must be accounted for such as the degree of risk involved, the magnitude of circumstances, as well as conditions or consequences that are not known or unpredictable. To circumvent binary views that cast uncertainty, the application of market research intelligence to strategically posture, move, and enable actionable outcomes is necessary.

View Methodology
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